超高效液相色谱-Orbitrap高分辨质谱用于减肥和壮阳类保健食品中32种非法添加药物的快速筛查和确证北大核心CSCD

建立了基于超高效液相色谱-Orbitrap高分辨质谱的快速筛查及确证减肥和壮阳类保健食品中32种非法添加药物的分析方法,并总结了数据库建立和应用的相关要点。研究对象聚焦于非法添加药物的衍生物,在对比正负离子模式下各化合物响应强度的基础上建立了高分辨质谱信息库,对提取溶剂、色谱柱温度等实验条件进行了详细探究,尽可能给出了较宽的标准曲线线性范围。使用Hypersil gold vanquish色谱柱(100 mm×2.1 mm,1.9μm),梯度洗脱,流量0.3 mL/min,正、负离子全扫描/数据依赖的二级扫描模式,在17 min内完成32种目标化合物的数据采集,通过TraceFinder软件进行快速定性筛查和定量。结果显示在17 min内32种化合物能得到较好分离;2种基质加标溶液中32种化合物的一级质谱离子精确质量数的实测值与理论值均在5×10^(-6)误差之内,二级碎片离子质量数的实测值与理论值均在1×10^(-5)误差之内;方法学验证结果表明,所有化合物均显示出优异的线性关系,相关系数(r^(2))均大于0.99;固体基质中除达泊西汀、羟基硫代豪莫西地那非、硫代豪莫西地那非、硫代西地那非、去甲基硫代西地那非的回收率较低外,其余27种化合物的回收率为50.5%~84.5%,相对标准偏差(RSD)为1.2%~13%,液体基质中32种化合物的回收率范围为60.4%~109.3%,RSD为0.77%~8.2%;在48份减肥及壮阳类保健食品中检出1份阳性样品,检出率2.08%。该方法操作简单,结果定性准确,可用于减肥及壮阳类保健食品中32种非法添加药物的快速筛查及确证。     

An experimental and numerical study of heave added mass and damping of horizontally submerged and perforated rectangular plates

Forced harmonic heave motions of horizontally submerged and perforated rectangular plates are studied experimentally and numerically at both a deep and shallow submergence. The steady-state vertical forces are expressed in terms of added mass and damping coefficients. The numerical results are partly obtained by combining potential flow with linear free-surface conditions and a nonlinear viscous pressure loss condition at the mean oscillatory plate position. A domain decomposition technique is applied with a boundary element method in the inner domain and an analytical representation of the velocity potential in the outer domain. A drag term accounts for the vortex shedding at the outer plate edges. The numerically predicted Keulegan–Carpenter number dependent heave added mass and damping coefficients agree reasonably with experimental values, in particular for the deeper submergence.     

加光子双模SU(2)相干光场的制备及其与Λ型三能级原子相互作用的性质

提出了通过对分束器的条件输出测量制备加光子双模SU(2 )相干光场的方案 ,并研究了Λ型三能级原子与此双模光场相互作用系统中 ,加光子对原子布居概率及光场非经典性质的影响。结果表明 ,原子粒子布居概率发生改变 ,光场一模的光子数统计趋向于亚泊松分布 ,另一模趋向于超泊松分布 ,光场两模间相关度增大 ,非经典相关程度增强。     

公路沿线基准地价评估的数学模型

从投资将导致地价增值的观点出发，建立了新建成改建公路沿线基准地价评估的分段指数递减的数学模型，采用“四三二一”法则建立了公路两侧不同纵深土地的基准地价评估的数学模型，并应用于宁波市江北区公路的基准地价评估，取得了较为满意的效果。     

Living cationic polymerization of dihydrofuran and its derivatives

Cationic polymerization of 2,3‐dihydrofuran (DHF) and its derivatives was examined using base‐stabilized initiating systems with various Lewis acids. Living cationic polymerization of DHF was achieved using Et_1.5AlCl_1.5 in toluene in the presence of THF at 0 °C, whereas it has been reported that only less controlled reactions occurred at 0 °C. Monomer‐addition experiments of DHF and the block copolymerization with isobutyl vinyl ether demonstrated the livingness of the DHF polymerization: the number–average molecular weight of the polymers shifted higher with low polydispersity as the polymerization proceeded after the monomer addition. Furthermore, this base‐stabilized cationic polymerization system allowed living polymerization of ethyl 1‐propenyl ether and 4,5‐dihydro‐2‐methylfuran at ?30 and ?78 °C, respectively. In the polymerization of 2,3‐benzofuran, the long‐lived growing species were produced at ?78 °C. The obtained polymers have higher glass transition temperatures compared to poly(acyclic alkyl vinyl ether)s. © 2008 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 4495–4504, 2008     

终身雇佣制评析

本文对终身雇佣制的特点，历史渊源和存在条件，当前面临的困境及相应的对策等进行了评析，期望为我国的人事劳动管理实践提供某些有益的启示。     

附加球面相位引致Airy光束在单轴晶体传输时的两次镜像演化

利用单轴晶体光束传输理论,求得了具有附加球面相位Airy光束在单轴晶体中的传输公式.数值模拟计算结果表明,线偏振附加球面相位Airy光束在晶体中传输时仍为线偏振,但不是传输不变的.粗略地讲,具有附加球面相位的Airy光束在晶体中传输时,近场是传输不变的;而在由晶体寻常与非寻常折射率和球面半径共同确定的两个特定传输距离处,传输光束转换成了取向不同的Gaussian-Airy光束,且高斯依赖的束宽度敏感地与截断因子相关;而当光束依次穿过此两位置时光斑花样先后相对于两横向轴平面做镜像演化,且镜像演化顺序也与晶体寻常和非寻常折射率相对大小密切相关,其总的效果是远场强度花样能恢复原样但花样取向产生了关于对过横平面二、四象限平分平面的镜像演化.这些结果表明,通过恰当选择晶体材料(即折射率)和附加球面相位的半径R,可以调控光束花样的形状、取向及表征各向异性材料的相关性质.     

Lower‐ and Higher‐Order Nonclassical Properties of Photon Added and Subtracted Displaced Fock States

Nonclassical properties of photon added and subtracted displaced Fock states are studied using various witnesses of lower‐ and higher‐order nonclassicality. Compact analytic expressions are obtained for the nonclassicality witnesses. Using those expressions, it is established that these states and the states that can be obtained as their limiting cases (except coherent states) are highly nonclassical as they show the existence of lower‐ and higher‐order antibunching and sub‐Poissonian photon statistics, in addition to the nonclassical features revealed through the Mandel $Q_M$ parameter, zeros of Q function, Klyshko's criterion, and Agarwal–Tara criterion. Further, some comparison between the nonclassicality of photon added and subtracted displaced Fock states have been performed using witnesses of nonclassicality. This has established that between the two types of non‐Gaussianity inducing operations (i.e., photon addition and subtraction) used here, photon addition influences the nonclassical properties more strongly. Further, optical designs for the generation of photon added and subtracted displaced Fock states from squeezed vacuum state have also been proposed.     

On the role of (weak) compressibility for fluid-structure interaction solvers

In the present study, a weakly compressible formulation of the Navier-Stokes equations is developed and examined for the solution of fluid-structure interaction (FSI) problems. Newtonian viscous fluids under isothermal conditions are considered, and the Murnaghan-Tait equation of state is employed for the evaluation of mass density changes with pressure. A pressure-based approach is adopted to handle the low Mach number regime, ie, the pressure is chosen as primary variable, and the divergence-free condition of the velocity field for incompressible flows is replaced by the continuity equation for compressible flows. The approach is then embedded into a partitioned FSI solver based on a Dirichlet-Neumann coupling scheme. It is analytically demonstrated how this formulation alleviates the constraints of the instability condition of the artificial added mass effect, due to the reduction of the maximal eigenvalue of the so-called added mass operator. The numerical performance is examined on a selection of benchmark problems. In comparison to a fully incompressible solver, a significant reduction of the coupling iterations and the computational time and a notable increase in the relaxation parameter evaluated according to Aitken's Δ² method are observed.